Large language models (LLMs) are revolutionizing health economics and outcomes research (HEOR), offering transformative possibilities in healthcare. Powered by generative AI, LLMs are reshaping pharmaceuticals and healthcare, from accelerating drug discovery to simplifying regulatory processes. While challenges exist, such as prompt quality and transparency, real-world examples demonstrate LLMs’ impact on drug discovery, clinical trial design, and regulatory affairs. Amaris Consulting leads this innovation, merging digital technology with HEOR expertise. Join us on this journey of discovery.